Congenital cytomegalovirus infection treated with idoxuridine.

Congenital cytomegalovirus infection treated with idoxuridine.

On 17 August he developed severe right iliac fossa pain, and the Mousseau-Barbin tube was removed at operation from the caecum, where it was found to be on the point of perforating the wall. On 6 September the oesophagotracheal fistulae were closed transoesophageally, through an incision in the right side of the neck. It was noted that a length of about 5 cm. of the right recurrent laryngeal ne...

Compartmentalized dynamics of cytomegalovirus replication in treated congenital infection.

BACKGROUND Cytomegalovirus (CMV) is the most prevalent congenital infection in developed countries. A significant number of infected infants develop long-term neurodevelopmental and hearing impairment irrespective of whether disease is detectable at birth. Studies of viral load and replication dynamics have informed the treatment of CMV in adult populations but no similar data exist in neonates...

Congenital cytomegalovirus virus infection.

A 14 months old male child with psychomotor retardation and hypotonia is reported, where computerized axial tomography revealed multiple calcification and ventriculomegaly secondary to cortical atrophy. Investigation suggested the diagnosis of cytomegalovirus infection. Importance of early diagnosis is emphasized as the potential long term sequelae can be prevented or reduced markedly with avai...

[Congenital cytomegalovirus infection].

Cytomegalovirus (CMV) belongs to the herpesvirus family. Its distribution is ubiquitous in man and many other mammals. CMV causes a typical cytopathic effect with enlargement of the cells that contain intranuclear and cytoplasmic inclusions. CMV is spread directly or by a contact with secretions. Nosocomial transmission can occur during blood transfusion or organ transplantation. Virus excretio...

Herpes simplex encephalitis treated with intravenous idoxuridine.